CDK4/6-IN-11 is a CDK4/CDK6 and IKZF1/IKZF3 degrader. CDK4/6-IN-11 induces G1-phase cell cycle arrest, reduces phosphorylated retinoblastoma protein levels, and exerts antiproliferative activity in mantle cell lymphoma cells, it is applicable to research related to mantle cell lymphoma.
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