Alloc-Val-Cit-PAB is a cathepsin B-cleavable linker used in Antibody-Drug Conjugate (ADC) research, featuring an Alloc-protected Valine-Citrulline dipeptide and p-aminobenzyl alcohol (PAB-OH). It acts as a stable, tumor-selective spacer that releases active payloads upon cleavage, commonly employed to connect antibodies to potent anticancer agents.
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