Biotin-S-S-amido-Propargyl-dUTP is a polymerase-compatible deoxyuridine triphosphate analog in which the uracil base is modified with a propargyl handle and conjugated via an amide-linked, cleavable disulfide spacer to biotin, enabling efficient DNA incorporation, high-affinity streptavidin-based detection or enrichment, and reversible DNA capture for sequencing, imaging, and nucleic acid–protein interaction studies.
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