N-(Azido-PEG8)-N-Boc-PEG8-t-butyl ester serves as a branched PEG linker, comprised of a terminal azide for copper-catalyzed click chemistry with alkynes and two terminal t-butyl ester groups, where the protected carboxyl group can be deprotected under acidic conditions. The PEG8 linkers bolster the hydrophilicity of the molecule. The branched structure allows for attachment of ADC payloads or other molecules.
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