Acid-PEG4-β-D-galactose is a versatile sugar PEG linker featuring a terminal carboxylic acid and a β-D-galactose moiety connected via a PEG4 spacer. The acid group enables efficient amide coupling with primary amines, while the PEG4 chain elevates solubility and molecular flexibility. The galactose unit provides receptor-mediated targeting capabilities, particularly valuable in glycoconjugate synthesis, drug discovery, and targeted therapeutics. This linker is ideal for applications such as bioconjugation, ADCs, and PROTAC design, where hydrophilicity and biological specificity are essential.
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