N-(amine-PEG4)-N-Boc-PEG4-t-butyl ester constitutes a branched PEG linker, including two terminal t-butyl-protected carboxyl groups, which can be deprotected under acidic conditions to free the acid, and a terminal amine group, which can be derivatized for further functionalization or conjugation. The PEG4 arms bolster the hydrophilicity of the molecule. The branched architecture supports the attachment of multiple ADC payloads or other entities.
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