BP Lipid 592 is a biodegradable ionizable lipid (pKa ~6.1) engineered for advanced LNP and liposome formulations. Its ester-cleavable backbone and dual hydrophobic tails—including two cis-unsaturated chain—enable efficient encapsulation of siRNA, mRNA, DNA, and small molecules, potent endosomal escape, and significantly reduced liver bioaccumulation compared to traditional lipids like MC3. Ideal for safer, high-performance gene therapy and vaccine delivery.
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