Fmoc-Gly-Gly-Gly-PEG2-DBCO is a cleavable tripeptide linker applied in the synthesis of antibody-drug conjugates (ADCs). The DBCO moiety serves as a handle for click chemistry, allowing it to react with azides. The Fmoc group can be deprotected under basic conditions to free the amine. The sulfo group and PEG8 linker enhance the molecule's water solubility and biocompatibility.
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