Ivosidenib
Ivosidenib (AG-120) is an orally active, selective inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1). It effectively reduces levels of the oncometabolite D-2-hydroxyglutarate (2-HG) in vivo by blocking its aberrant production. Ivosidenib promotes cellular differentiation and inhibits proliferation in tumor cells harboring IDH1 mutations. With a favorable safety profile and demonstrated clinical activity, it holds therapeutic potential for the treatment of acute myeloid leukemia (AML) and other mIDH1-associated malignancies. Reagent grade, for research use only.

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Catalog:
BP-43660
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Name:
Ivosidenib
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Formula:
C28H22ClF3N6O3
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MW:
583
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CAS:
1448347-49-6
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Purity:
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Ships Within:
24 Hours
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Storage Condition:
-20°C
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Shipping:
Ambient Temperature
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NMR:
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SDS:
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