Ara-guanosine Triphosphate (Ara?GTP), the arabinofuranosyl guanine 5′?triphosphate of nelarabine, pairs a 2′?inverted arabinosyl sugar, guanine base, and high?energy γ?β?α phosphates, seamlessly replacing dGTP in DNA to halt polymerases and provoke lethal strand damage. Reagent grade, for research use only.
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