Aldehyde-PEG4-bis-PEG3-azide is a branched, water-soluble PEG linker ideal for increased payload capacity in ADCs. Its aldehyde group reacts with hydrazide/amine groups to form hydrazone/imine bonds, while the two azide groups enable click chemistry with BCN, DBCO, or alkynes. The PEG spacers enhance solubility.
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