DSPE-PEG36-NH-Mal is an amphiphilic, monodisperse PEG-phospholipid that features a maleimide functional group, allowing for site-specific conjugation to thiol-containing molecules. With its hydrophilic PEG spacer and hydrophobic lipid tails, it readily self-assembles into lipid bilayers or micelles in aqueous environments. This makes it a valuable component in drug delivery systems, including liposomes used in mRNA and DNA vaccines, where it facilitates both structural stability and targeted functionalization.
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