Hydrocortisone acetate is the synthetic acetate salt of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties. It binds to the cytoplasmic glucocorticoid receptor, forming a complex that translocates to the nucleus and promotes the transcription of anti-inflammatory mediators such as cytokines and lipocortins. Lipocortins inhibit phospholipase A2, preventing arachidonic acid release and blocking the synthesis of prostaglandins and leukotrienes.
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