Monophosphoryl Lipid A-504 was designed as a synthetic structural analog of detoxified MPLA derived from E. coli lipopolysaccharide (LPS). It is structurally similar to PHAD, differing only in the length of a single fatty acid chain. As expected, the activity of PHAD-504 is quite similar to that of PHAD, making the two products interchangeable as adjuvants in vaccine or immunotherapy formulations.
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