Biotin-S-S-PEG3-Azide functions as a cleavable reagent for biotinylating proteins or cell surfaces with primary amines. Its disulfide bond enables biotin removal using reducing agents like DTT, BME, or TCEP, ensuring reversible labeling for dynamic studies. The azide can partake in click reactions reactions with alkyne, BCN, and DBCO. The PEG units improve the water solubility of the molecule.
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