Cholesterol-3,4-13C2 is an isotopically labeled form of cholesterol, with 13C atoms at the carbon-3 and carbon-4 positions, designed for use as an internal standard in the quantification of cholesterol via GC- or LC-MS. Cholesterol is a key sterol in mammalian cells essential for cell viability and proliferation. It is a critical component of cell membranes, interacting with phospholipids, sphingolipids, and proteins to regulate membrane dynamics and functionality. Cholesterol also plays a vital role in lipid-based drug delivery (LBDD) systems, such as liposomes and lipid nanoparticles (LNPs), where it contributes to membrane stability. Additionally, it serves as a precursor for steroid hormones, bile acids, and active vitamin D. Disruptions in cholesterol homeostasis are linked to numerous health conditions, including fatty liver disease, diabetes, gallstones, dyslipidemia, atherosclerosis, heart attacks, and strokes.
Usually ships within 24 hours.