BP Lipid 458 is a cationic ionizable lipid ALC-0315 analogue featuring a Boc-protected primary amine, a central tertiary amine, and two ester tails located at the C8 position relative to the amine. These esters feature symmetrical branched C17 tails. Ionizable lipids such as this may be applied in the development of lipid nanoparticles for drug delivery.
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