L-threo-sphingosine (d18:1)

L-threo-sphingosine (d18:1)


L-threo-sphingosine (d18:1), an analog of D-erythro-sphingosine, inhibits protein kinase C with 50% inhibition at 2.2 mol%, making it slightly more potent than D-erythro-sphingosine (50% inhibition at 2.8 mol%) and other analogs with shorter alkyl chains. Unlike D-erythro-sphingosine, L-threo-Sphingosine C-18 does not reduce serine palmitoyltransferase (SPT) activity, the rate-limiting enzyme in ceramide biosynthesis, in primary cultured cerebellar cells.

Molecular structure of the compound BP-42457
    • Unit
    • Price
    • Qty
    • 5 MG
    • $190.00
    • 10 MG
    • $340.00
    • 25 MG
    • $640.00
    • 50 MG
    • $1200.00

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