Sphingomyelin, a key component of cell membranes, is especially concentrated in nerve cell myelin sheaths and red blood cells. Once believed to have a purely structural role, it is now known to interact with cholesterol, forming lipid rafts that regulate protein signaling and localization. Additionally, sphingomyelin serves as a precursor to ceramides and other sphingolipid metabolites in the sphingomyelin cycle.
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