ARD-1676 is an orally bioavailable PROTAC designed for degrading the androgen receptor (AR). It comprises a ligand that targets AR and a cereblon ligand, facilitating the degradation process through the ubiquitin-proteasome system. This compound demonstrates effective AR degradation both in vitro and in vivo, contributing to the inhibition of tumor growth in mouse xenograft models. Reagent-grade; for laboratory research purposes only.
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