L-Homopropargylglycine (HPG) is a noncanonical amino acid analog of methionine featuring a terminal alkyne group. HPG is cell-permeable and randomly integrates into growing proteins during translation, replacing methionine. The resulting alkyne-labeled full-length proteins can be identified through copper-catalyzed click reactions with fluorescent or biotin-labeled azides. These labeled proteins are then suitable for various applications such as microscopic imaging or purification.
Usually ships within 24 hours.