3,4-Dibromo-Mal-PEG8-Boc-Amine functions as a site-specific ADC linker with a dibromomaleimide group and boc-protected amine that can be hydrolyzed under acidic conditions to produce a free amine which is reactive to an activated succinimidyl (NHS) ester. The dibromomaleimide group allows for two points of substitution due to the two bromine atoms. Dibromo-Maleimide is sensitive to high temperature and light. The hydrophilic PEG8 spacer improves the aqueous solubility of the compound and aids in optimizing DMPK properties. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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