DSPE-Hyd-PEG-MAL, MW 2,000 constitutes a phospholipid polyPEG with a hydrazone moiety, which can self-assemble to form a lipid bilayer in aqueous solution. The polymer can be used to prepare liposomes as a drug delivery vehicle. Hydrazone linkages are useful for coupling drugs to targeted antibodies where the linkage is stable at neutral pH, but is rapidly destroyed in the acidic environment of lysosomes of the cell. The maleimide moiety can react with cysteine or other thiol-bearing molecules for bioconjugation. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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