(1,3-dioxoisoindolin-2-yl)-PEG3-amine serves as a unique PROTAC linker, featuring a thalidomide analog, hydrophilic PEG spacer, and free amine to readily react with an activated NHS ester. Thalidomide recruits E3 Ligase for the ubiquitinylation and subsequent destruction of a given protein. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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