Azido-PEG-NHS ester, MW 5,000

Azido-PEG-NHS ester, MW 5,000


Azido-PEG-NHS ester, MW 5,000 (N3-PEG-SPA, MW 5,000) is an active ester containing an azide group. Azide is reactive with alkyne, DBCO, BCN… through Click chemistry. Azido-PEG-NHS ester offers several benefits over the Azido-PEG-CH2CO2-NHS. Azido-PEG-NHS ester is more stable in aqueous solutions compared to Azido-PEG-CH2CO2-NHS. It is a better choice for conjugations that are to be performed in aqueous solutions. Azido-PEG-NHS ester (N3-PEG-SPA) is also more stable for storage than Azido-PEG-CH2CO2-NHS (N3-PEG-SCM). Azido-PEG-NHS ester is reactive with primary amine but at a lower rate compared to Azido-PEG-CH2CO2-NHS.

Molecular structure of the compound BP-40968
    • Unit
    • Price
    • Qty
    • 50 MG
    • $250.00
    • 100 MG
    • $450.00
    • 250 MG
    • $750.00
    • 500 MG
    • $1200.00

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Product Citations


  1. Jeon, J. H., Cheon, S. Y., Park, S. H., Lee, H., Yoo, S. Y., Ahn, M. Y., ... & Kim, S. W. (2025). Lacuna-mimic human-derived nasal septal chondrocyte clusters encapsulated in click chemistry-based hydrogel for in vivo cartilage regeneration. Chemical Engineering Journal, 165965.
    https://www.sciencedirect.com/science/article/abs/pii/S1385894725068032