DSPE-PEG6-Mal is a PEG linker with a maleimide group, water-soluble PEG chain, a hydrophilic phosphate head with hydrophobic lipid tails. The polymer can self-assemble to form lipid bilayer in water. The phospholipid polyPEG can be used as a drug nanocarrier for administration of nutrients and therapeutic drugs, such as liposomes in mRNA or DNA vaccines. The maleimide group will react with a thiol group to form a covalent bond.
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