Thalidomide-NH-C6-NH-Boc

Thalidomide-NH-C6-NH-Boc

Thalidomide-NH-C6-NH-Boc is a PROTAC linker featuring a thalidomide, a hydrophilic PEG spacer, and a Boc-protected amine. Thalidomide is an E3 ligase activator, promoting the ubiquitinylation of a given protein. Meanwhile, the Boc protecting group may be removed to reveal a primary amine which reacts with a variety of substrates.

Molecular structure of the compound BP-40557
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