Pomalidomide-amido-C3-COOH is a PROTAC linker featuring a pomalidomide, a pentyl spacer, and a carboxylic acid. Pomalidomide recruits E3 ligase for the ubiquitinylation and subsequent proteolysis of a given protein. Meanwhile, the carboxylic acid may react with amines in the presence of coupling reagents such as EDC or HATU.
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