3,4-(PEG4-Azide)-2-((PEG4-Azide)methyl)propan-1-ol is a multifunctional reagent combining three azides and a primary alcohol. The azide group is commonly used in click chemistry for reactions with terminal alkynes as well as strained cyclooctynes such as BCN or DBCO. The primary alcohol is a useful scaffold for building molecular complexity such as for creating esters or substitution with any number of functional groups. The use of a PEG linker increases this compound’s aqueous solubility, altering its DMPK properties in drug development.
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