N-(Mal-PEG4-carbonyl)-N-bis(PEG4-acid) is a bifunctional reagent with two carboxylic acids and a maleimide group. Maleimide is a thiol-specific covalent ligand that is often used in labeling proteins, while the carboxylic acids are open for reaction with primary amines to form amide bonds. PEG linkers are highly water soluble but the inclusion of an amide bond makes this molecule especially so.
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