N-(DBCO-PEG4-carbonyl)-N-bis(PEG4-NHS ester) is a chemical linker that contains two NHS esters and a DBCO group. DBCO is a strained cyclooctyne that is used in a click reaction with azides to form stable triazole links, while the NHS esters are highly activated towards reactions with amines and alcohols. The use of a tertiary amide increases the water solubility of this compound.
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