N-(Azide-PEG8-carbonyl)-N-bis(PEG8-t-butyl ester)

N-(Azide-PEG8-carbonyl)-N-bis(PEG8-t-butyl ester)

N-(Azide-PEG8-carbonyl)-N-bis(PEG8-t-butyl ester) is a trifunctional reagent with two t-butyl ester and an azide. The azide group can be used to label terminal alkynes and strained cyclooctynes like BCN or DBCO using click chemistry. The t-butyl esters can be deprotected using acid or base to allow for attack from amines or alcohols. The central junction is a tertiary amide, allowing for hydrogen bonding effects to increase this molecule’s aqueous solubility.