Thalidomide-O-PEG8-Amine, HCl salt

Thalidomide-O-PEG8-Amine, HCl salt


Thalidomide-O-PEG8-Amine, HCl salt is a PROTAC linker featuring a thalidomide ligand and a primary amine connected by a PEG chain. Primary amines readily form amides with carboxylic acids in the presence of coupling reagents. Thalidomide is a ligand for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction.

Molecular structure of the compound BP-40376
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    • 100 MG
    • $540.00
    • 250 MG
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    • 500 MG
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