Thalidomide

Thalidomide


Thalidomide serves as a ligand in PROTAC development, recruiting the Cereblon (CRBN) E3 ligase complex to the target protein. This recruitment brings the target protein and E3 ligase into close proximity, resulting in polyubiquitination of the substrate and subsequent degradation by the proteasome

Molecular structure of the compound BP-30256
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    • 5 G
    • $110.00
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    • 25 G
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