t-butyl-C18-D-Glu-OtBu-PEG2-acid is a PEG linker comprised of an octadecanedioic acid and a glutamic acid, which is also protected by a terminal t-butyl ester. The t-butyl groups can be deprotected under acidic conditions. Glutamic acid is an α-amino acid that is used in the biosynthesis of proteins. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond. Reagent grade, for research use only.
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