Azide-Polysarcosine150
Azide-Polysarcosine150 is a lipid-polypeptoid conjugate based on the endogenous amino acid sarcosine (N-methylated glycine) with an average of 150 sarcosine units. The azide can undergo copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN. Polysarcosine has been shown to have a higher protein secretion with a reduced immunostimulatory response observed when compared to systems based on polyethylene glycol (PEG) lipids. Azide-Polysarcosine can be used to create lipids for the formation of lipid nanoparticles (LNPs) to be used in therapeutic applications of mRNA.

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Catalog:
BP-28440
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Name:
Azide-Polysarcosine150
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Formula:
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MW:
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CAS:
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Purity:
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Ships Within:
24 Hours
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Storage Condition:
-20°C
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Shipping:
Ambient Temperature
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Availability:
In Stock
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NMR:
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SDS:
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