DBCO-PEG12-para-phenylboronic acid is a click chemistry reagent with a DBCO group and a terminal Phenyl boronic acid. The DBCO can undergo copper-free Click Chemistry reactions with azides. Phenyl boronic acid (PBA) moiety has been most widely studied and used in the construction of glucose-responsive systems for insulin delivery. Additionally, PBA materials have been used to prepare nanoparticles/micelles for delivering therapeutic agents, such as proteins, siRNA, anti cancer agent, etc. The hydrophilic PEG linker increases the water solubility of the compound. Reagent grade, for research use only.
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