DSPE-PEG-Boronate, MW 3,400 is a phospholipid PEG polymer which can form lipid bilayer in aqueous solution. Phenyl boronic acid (PBA) moiety has been most widely studied and used in construction of glucose-responsive systems for insulin delivery. Additionally, PBA materials have been used to prepare nanoparticles/micelles for delivering therapeutic agents, such as proteins, mRNA, siRNA, etc.
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