PLGA(2k)-PEG(1k)-MAL is a thiol reactive amphiphilic polymer. The conjugation between maleimide and thiol forms a stable thioether bond. The polymer contains a hydrophobic block (poly(lactide-co-glycolide) (PLGA)) and a hydrophilic block (PEG) which can form micelles in water. This class of polymer can be used to prepare vesicle for drug delivery application.
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