PLGA(10k)-PEG(5k)-ALK is a polymer with both hydrophobic (poly(lactide-co-glycolide)/PLGA) and hydrophilic (PEG) blocks. The self-assembly of the polymer in water occurs with PLGA being shielded at the core by PEG shell. The hydrophobic core can be used to encapsulate lipophilic drugs while the PEG shell offers protection against (enzymatic/hydrolysis) degradation in drug delivery/nanomedicine.
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