NI 57

NI 57


NI-57 is a selective and potent inhibitor of BRPF (Bromodomain and PHD Finger) family of proteins (BRPF1/2/3). NI 57 shows Kd values of 31, 108 and 408 nM, for BRPF1B, 2 and 3, respectively. NI 57 also exhibits >32-fold selectivity for BRPFs over BRD9 and other non-Class IV bromodomains. Inhibits RANKL-induced differentiation of primary murine bone marrow cells and human primary monocytes into osteoclasts. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-25365
    • Unit
    • Price
    • Qty
    • 10 MG
    • $160.00
    • 25 MG
    • $360.00

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