N-Mal-N-bis(PEG4-acid) is an Maleimide PEG reagent with two terminal carboxylic acids and a maleimide (Mal) group. Maleimide (Mal) reacts specifically with sulfhydryl groups to form a stable thioether linkage when the pH is between 6.5 and 7.5. The terminal carboxylic acids can conjugate with iamine-containing molecule in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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