TAMRA-PEG4-Tetrazine
TAMRA-PEG4-Tetrazine is a tatrazine attached tetramethylrhodamine (TAMRA) dye. Rhodamine is a commonly used red fluorescent dye tracer in biology for staining cells, tissues, biomarkers or nanoparticles. It has peak fluorescence emission at 572-575 nm. Tetrazin demonstrates exceptionally fast cycloaddition kinetics (up to 30 000 M-1 s-1) with trans-cyclooctene (TCO) as the dienophile, the fastest kinetics ever reported for any bioorthogonal reaction. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Product Citations
- Auger, S. A., Venkatachalapathy, S., Suazo, K. F. G., Wang, Y., Sarkis, A. W., Bernhagen, K., ... & Distefano, M. D. Supporting Information Broadening the utility of farnesyltransferase-catalyzed protein labeling using norbornene-tetrazine click chemistry.
https://plueckthun.bioc.uzh.ch/wp-content/uploads/Publications/Supp0533.pdf - Zaleski, M. H., Chase, L. S., Hood, E. D., Wang, Z., Nong, J., Espy, C. L., ... & Brenner, J. S. (2025). Conjugation Chemistry Markedly Impacts Toxicity and Biodistribution of Targeted Nanoparticles, Mediated by Complement Activation. Advanced Materials, 37(5), 2409945.
https://doi.org/10.1002/adma.202409945