DBCO-S-S-PEG3-biotin is a cleavable reagent for introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. PEG spacer arm provides better solubility to the labeled molecules in aqueous media. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-22453
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Product Citations

  1. Burgess, J.D., Amerna, D., Norton, E.S. et al. A mutant methionyl-tRNA synthetase-based toolkit to assess induced-mesenchymal stromal cell secretome in mixed-culture disease models. Stem Cell Res Ther 14, 289 (2023). https://doi.org/10.1186/s13287-023-03515-0
  2. Norton, E. S., Whaley, L. A., Jones, V. K., Brooks, M. M., Russo, M. N., Morderer, D., ... & Guerrero-Cazares, H. (2023). Cell-specific crosstalk proteomics reveals cathepsin B signaling as a driver of glioblastoma malignancy near the subventricular zone. bioRxiv, 2023-08.