t-Boc-N-amido-PEG4-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-21635
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Product Citations

  1. Van der Beelen SHE, Agten SM, et al. Design and synthesis of a multivalent catch-and-release assay to measure circulating FXIa. Thrombosis Research. 2021. 200. pp. 16-22.