Azido-PEG4-acid

Azido-PEG4-acid

Azido-PEG4-acid is a very popular PEG reagent containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-20517
    • Unit
    • Price
    • Qty
    • 250 MG
    • $170.00
    • 500 MG
    • $270.00
    • 1 G
    • $410.00
    • 5 G
    • $1580.00

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Product Citations

  1. Bataille Backer, P., Adekiya, T. A., Kim, Y., Reid, T. E. R., Thomas, M., & Adesina, S. K. (2024). Development of a Targeted SN-38-Conjugate for the Treatment of Glioblastoma. ACS Omega.
    https://pubs.acs.org/doi/full/10.1021/acsomega.3c07486
  2. Owoseni, O. B. (2023). Development of Dual-Drug Conjugate Loaded Nanoparticle Platform for Site-Specific Delivery to Prostate Cancer (Doctoral dissertation, Howard University).
    https://www.proquest.com/openview/39bd0b22805503b3d4b4fd4d10d03dda/1?pq-origsite=gscholar&cbl=18750&diss=y
  3. Tallon, Carolyn, Benjamin J. Bell, Anjali Sharma, Arindom Pal, Medhinee M. Malvankar, Ajit G. Thomas, Seung-Wan Yoo et al. Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice. Pharmaceutics. 2022
    https://www.mdpi.com/1999-4923/14/10/2066
  4. Tallon, Carolyn; Bell, Benjamin J; Sharma, Anjali; Pal, Arindom; Malvankar, Medhinee M; et al.  Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice. Pharmaceutics. 2022 Vol 12, Iss 10
    https://www.proquest.com/openview/1fb23c42177a78fb789c1971290de0ae/1?pq-origsite=gscholar&cbl=2032349