BP Lipid 312
BP Lipid 312 is a proprietary ionizable lipid developed by BroadPharm, designed for comparison with lipid LP01 and other related lipids. It features a key structural modification—the substitution of a polyunsaturated tail with a monounsaturated equivalent—which may influence lipid nanoparticle performance. BP Lipid 312 has been utilized in the formulation of lipid nanoparticles (LNPs) for the delivery of CRISPR-Cas9 RNA, as demonstrated in product citations (see below). This product is provided at reagent grade, intended for research use only. For inquiries regarding GMP-grade material, please contact us directly.
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Catalog:
BP-40215
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Name:
BP Lipid 312
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Formula:
C48H91NO9
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MW:
826.3
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CAS:
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Purity:
95%
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Ships Within:
24 Hours
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Storage Condition:
-20°C
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Solubility:
DMSO, DCM, DMF
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Shipping:
Ambient Temperature
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Availability:
In Stock
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NMR:
View
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SDS:
Inquire about MSDS
Product Citations
- Chen, K., Han, H., Zhao, S., Xu, B., Yin, B., Lawanprasert, A., ... & Doudna, J. A. (2024). Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR–Cas9 ribonucleoprotein. Nature Biotechnology, 1-13.
https://www.nature.com/articles/s41587-024-02437-3
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LP01
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BP Lipid 566
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VL422
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Ionizable Lipid 4