C12-200

C12-200

C12-200 is a branched-chain ionizable lipidoid with five hydroxyl groups. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA, siRNA, or self-amplifying RNA (saRNA). The hydroxyl groups enables further derivatization or replacement with other reactive functional groups. Reagent grade, for research use only.

Molecular structure of the compound BP-26474
    • Unit
    • Price
    • Qty
    • 25 MG
    • $280.00
    • 50 MG
    • $540.00
    • 100 MG
    • $860.00
    • 250 MG
    • $1500.00

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Product Citations

  1. Coussens, E. Exploring the potential of CRISPR/Cas9 lipid nanoparticles to cure HIV.
    https://lib.ugent.be/catalog/rug01:003212736
  2. Hussain, M., Binici, B., O’Connor, L., & Perrie, Y. (2024). Production of mRNA lipid nanoparticles using advanced crossflow micromixing. Journal of Pharmacy and Pharmacology, 76(12), 1572-1583.
    https://academic.oup.com/jpp/article/76/12/1572/7816331
  3. Lindsay, S., Hussain, M., Binici, B., & Perrie, Y. (2025). Exploring the challenges of lipid nanoparticle development: the in vitro–in vivo correlation gap. Vaccines, 13(4), 339.
    https://www.mdpi.com/2076-393X/13/4/339