DSPC
DSPC (1,2-distearoyl-sn-glycero-3-phosphocholine) is a phosphatidylcholine with saturated tails. It has a melting temperature of ~54°C and a cylindrical geometry that allows DSPC molecules to form a lamellar phase, which stabilizes the structure of lipid nanoparticles. DSPC has been used in the mRNA-1273 and BNT162b2 COVID-19 vaccines. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Product Citations
- Kim, B., Seo, H. W., Lee, K., Yong, D., Park, Y. K., Lee, Y., ... & Ryu, C. M. (2024). Lipid Nanoparticle?Mediated CRISPR?Cas13a Delivery for the Control of Bacterial Infection. Advanced Healthcare Materials, 2403281.
https://doi.org/10.1002/adhm.202403281 - Li, Y., Ambati, S., Meagher, R. B., & Lin, X. (2025). Developing mRNA lipid nanoparticle vaccine effective for cryptococcosis in a murine model. npj Vaccines, 10(1), 24.
https://www.nature.com/articles/s41541-025-01079-z