DM4
Ravtansine (DM4) is a chemical derivative of maytansine which is used as a cytotoxic component of antibody-drug conjugates. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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Catalog:
BP-23649
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Name:
DM4
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Formula:
C38H54ClN3O10S
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MW:
780.4
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CAS:
796073-69-3
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Purity:
98%
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Ships Within:
24 Hours
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Storage Condition:
-20°C
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Shipping:
Ambient Temperature
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Availability:
In Stock
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NMR:
View
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SDS:
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Product Citations
- Verhaar, E. R. (2024). Targeting MHC-I related proteins for cancer diagnosis and therap (Doctoral dissertation, Leiden University).
https://scholarlypublications.universiteitleiden.nl/handle/1887/3766089 - Verhaar, E. R., Knoflook, A., Pishesha, N., Liu, X., van Keizerswaard, W. J., Wucherpfennig, K. W., & Ploegh, H. L. (2024). MICA-specific nanobodies for diagnosis and immunotherapy of MICA+ tumors. Frontiers in Immunology, 15, 1368586.
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1368586/full - Wucherpfennig, K. W., & Ploegh, H. L. (2024). MICA-specific nanobodies for diagnosis and immunotherapy of MICA+ tumors. Cell Death in Cancer Immunology.
https://books.google.com/books?hl=en&lr=&id=usc0EQAAQBAJ&oi=fnd&pg=PA51&dq=broadpharm&ots=vs31P2bUPp&sig=VqIK6XawpYpPeQs2QQp6WQhR-cw#v=onepage&q=broadpharm&f=false - Zhang X, Zhang C, et al. Design, synthesis and evaluation of anti-CD38 antibody drug conjugate based on Daratumumab and maytansinoid. Bioorganic & Medicinal Chemistry. 2019. 27(3). pp. 479-482.
https://www.sciencedirect.com/science/article/pii/S0968089618316201